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CAS 300-85-6 BHB Beta-Hydroxybutyrate powder
What is Beta Hydroxybutyrate?
Beta-hydroxybutyric acid is a small molecule substance naturally produced by the human body when it breaks down fat. In the first six months after birth, newborns mainly absorb nutrients needed for growth through breast milk. Babies break down fat from breast milk to produce beta-hydroxybutyric acid, which provides the energy needed for body and brain functioning. For adults, it only occurs under circumstances such as hunger, overnight fasting, inedia, strenuous exercise, or a specific diet.
BHB working principle
Beta-hydroxybutyric acid works primarily through the following pathways:
Energy Production: Beta-hydroxybutyric acid is able to be utilized by the body as an energy source, especially when carbohydrate supplies are low. It can be converted into acetyl-CoA through the ketone body synthesis pathway in the liver, and then enter the tricarboxylic acid cycle to produce ATP to provide energy for the body.
Neuroprotective effect: It has a protective effect in the nervous system, inhibiting nerve cell apoptosis, reducing oxidative stress damage, and improving the metabolic adaptability of neurons.
Appetite suppression: Ketone bodies suppress appetite by affecting neurotransmitters and neuron activity, helping to control weight and reduce hunger.
When the glucose in the human body is too low, the body will mobilize the liver to produce ketone bodies by decomposing fatty acids in the blood (mainly composed of beta hydroxybutyrate + acetoacetate + acetone, more than 70% of which are BHB), and are composed of The blood is transported to various tissues and cells in the body, enters the cell mitochondria for ketolysis and is converted into acetyl-CoA, and enters the tricarboxylic acid cycle to generate energy (ATP). Exogenous supplementation of BHB can also play the same role, so it is called an important energy source for the body.
BHB is gradually becoming known to the public as an energy substance. For our bodies, BHB is a small molecule substance naturally produced in the process of human body fat metabolism to provide energy. It will exist in the human body in large quantities especially before babies are weaned, providing the body and brain needs of babies who are not yet able to eat normally. part of the energy to ensure the healthy growth of the baby.
For adults, under conditions such as hunger, overnight fasting, fasting, strenuous exercise, or a specific diet, the glucose in the body is too low and cannot supply the body's energy needs. At this time, the body will mobilize the liver to break down fat in the body. Provide the energy needed by the human body.
The process of fat metabolism in the liver to generate BHB and BHB metabolism in organs outside the liver to generate energy is shown in the figure below. After it is generated in the liver, it is transported to the cells of various tissues and organs of the body through the blood, and is converted to ketosis in the mitochondria of the cells. It is acetyl coenzyme A and enters the tricarboxylic acid cycle to produce energy (ATP). Exogenous supplementation of BHB can provide energy to the human body without going through the above-mentioned suffering process, so it is called the body's "new energy source".
Application direction
Beta hydroxybutyric acid is widely used in the fields of medical health products and nutritional supplements
It can improve the brain's cognitive ability and memory level, prevent and alleviate Alzheimer's disease, delay vascular aging, prevent osteoporosis, enhance aerobic exercise endurance and help the body repair after exercise, treat obesity, and improve depressive behavior and autism, etc.
