98% Nicotinamide riboside NR Powder

Nicotinamide riboside is the precursor of nicotinamide adenine dinucleotide (NAD) and represents a source of vitamin B3. Recent research has shown that consuming greater amounts of nicotinamide riboside than naturally found in foods may result in new health benefits. Nicotinamide mononucleotide plays an important role in the energy production of human cells. It participates in the synthesis of intracellular NAD (nicotinamide adenine dinucleotide, an important coenzyme for cellular energy conversion).

Nicotinamide riboside chloride is a crystalline form of nicotinamide riboside (NR) chloride that is generally recognized as safe (GRAS) for use in foods and dietary supplements. Nicotinamide riboside is a source of vitamin B3 (nicotinic acid), which can enhance oxidative metabolism and prevent metabolic abnormalities caused by high-fat diet. Nicotinamide riboside is a newly discovered NAD (NAD+) precursor vitamin.

NAD+ is a coenzyme or accessory molecule involved in many biological reactions.

Research shows that NAD+ levels continue to decline with age. Lower NAD+ levels are associated with aging and various harmful diseases.

One way to increase NAD+ levels is to consume NAD+ precursors (the building blocks of NAD+) such as nicotinamide riboside.

Animal studies show that nicotinamide ribose can increase the amount of NAD+ in the blood by up to 2.7 times. What’s more, it’s easier for your body to use than other NAD+ precursors (7Trusted Source).

Nicotinamide Ribose helps increase NAD+ levels in the body.

In response, NAD+ activates certain enzymes that promote healthy aging.

One is sirtuins, which improve an animal's lifespan and overall health. Research shows that sirtuins can repair damaged DNA, increase stress resistance, reduce inflammation and provide other benefits that promote healthy aging. Sirtuins are also responsible for limiting calories for life.

The other is poly(ADP-ribose) polymerase (PARP), which repairs damaged DNA. Research links higher PARP activity to less DNA damage and longer lifespan.

NAD+ plays a key role in helping your brain cells age.

Within brain cells, NAD+ helps control the production of PGC-1-alpha, a protein that appears to help protect cells from oxidative stress and impaired mitochondrial function.

In mice with Alzheimer's disease, nicotinamide riboside increased brain NAD+ levels and PGC-1-alpha production by 70% and 50%, respectively. By the end of the study, the mice performed significantly better on memory-based tasks.

In a test-tube study, nicotinamide riboside increased NAD+ levels in stem cells from Parkinson's disease patients and significantly improved mitochondrial function

In animals, raising NAD+ helps reverse age-related changes in arteries.

In humans, nicotinamide riboside increases NAD+ levels and helps reduce aortic stiffness and lower systolic blood pressure in adults at risk for hypertension. However, more human studies are still needed.

In addition, nicotinamide riboside may provide several other benefits:

May help with weight loss: Nicotinamide ribose helps speed up metabolism in mice.

May Help Treat Jet Lag: NAD+ Helps Regulate the Body's Internal Clock

May Promote Healthy Muscle Aging: Raising NAD+ levels helps improve muscle function, strength and endurance in aged mice.

Nicotinamide riboside chloride is a crystalline form of nicotinamide riboside (NR) chloride that is generally recognized as safe (GRAS) for use in foods and dietary supplements. Nicotinamide riboside is a source of vitamin B3 (nicotinic acid), which can enhance oxidative metabolism and prevent metabolic abnormalities caused by high-fat diet. Nicotinamide riboside is a newly discovered NAD (NAD+) precursor vitamin.

It has been implicated in increasing tissue NAD concentrations and inducing insulin sensitivity as well as enhancing sirtuin function. Its ability to increase NAD production suggests that nicotinamide riboside may also improve mitochondrial health, stimulate mitochondrial function and induce the production of new mitochondria. Other studies using nicotinamide riboside in Alzheimer's disease models have shown that the molecule is bioavailable to the brain and may provide neuroprotection by stimulating brain NAD synthesis.